The Natural History of Full-Thickness Rotator Cuff Tears in Randomized Controlled Trials: A Systematic Review and Meta-analysis.

BACKGROUND: Rotator cuff tears are the most common tendon injury in the adult population, resulting in substantial morbidity. The optimum management for these patients is not known. PURPOSE: To assess the overall treatment response to all interventions in full-thickness rotator cuff tears among patients enrolled in randomized clinical trials. STUDY DESIGN: Systematic review and meta-analysis. METHODS: Randomized controlled trials (RCTs) were identified from a systematic search of Medline, Embase, CINHAL, and the Cochrane Central Register of Controlled Trials. Patients were aged ≥18 years with a full-thickness rotator cuff tear. The primary outcome measure was change in Constant shoulder score from baseline to 52 weeks. A meta-analysis to assess treatment response was calculated via the standardized mean change in scores. RESULTS: A total of 57 RCTs were included. The pooled standardized mean change as compared with baseline was 1.42 (95% CI, 0.80-2.04) at 3 months, 2.73 (95% CI, 1.06-4.40) at 6 months, and 3.18 (95% CI, 1.64-4.71) at 12 months. Graphic plots of treatment response demonstrated a sustained improvement in outcomes in nonoperative trial arms and all operative subgroup arms. CONCLUSION: Patients with full-thickness rotator cuff tears demonstrated a consistent pattern of improvement in Constant score with nonoperative and operative care. The natural history of patients with rotator cuff tears included in RCTs is to improve over time, whether treated operatively or nonoperatively.

Significance of Perioperative Tests to Diagnose the Infection in Revision Total Shoulder Arthroplasty.

BACKGROUND: The purpose of this study was to evaluate the value of perioperative tests for the diagnosis of infection in revision shoulder arthroplasty. METHODS: A retrospective analysis was performed on 537 shoulder arthroplasties (429 patients) that underwent revision shoulder arthroplasty at our institution. Periprosthetic tissue cultures were positive in 169/537 surgeries. RESULTS: White-blood cell count (WBC) was elevated in 3.8% revision arthroplasties. Erythrocyte sedimentation rate (ESR) was elevated in 23.1% revision arthroplasties. The C-reactive protein (CRP) was elevated in 20.8% revision arthroplasties. Bone scans (technetium, indium) were performed on 9.9% patients and it was positive for osteomyelitis in just one revision arthroplasty. Intra-operative pathology was read as consistent with acute inflammation in 11.9% revision arthroplasties. The positive and negative predictive values for intra-operative pathology were 56.7% and 71.6% respectively. CONCLUSION: All of the perioperative tests had a high specificity and negative predictive value, but low sensitivity and positive predictive value.

Distal Biceps and Triceps Injuries.

BACKGROUND: Rupture of the distal biceps and triceps tendons are relatively uncommon injuries typically occurring in middle-aged males as a result of eccentric loading of the tendon. METHODS: A literature search was performed and the authors' personal experiences reported. RESULTS: This review discusses the diagnosis, indications and guidelines for management of these injuries and provides a description of the authors' preferred operative techniques. CONCLUSION: Whilst non-operative treatment may be appropriate for patients with low functional demands, surgical management is the preferred option for the majority of patients. We have described a cortical button technique and osseous tunnel technique utilised at our institution for distal biceps and triceps tendon fixation respectively. For biceps or triceps tendon injuries, those receiving an early diagnosis and undergoing surgical intervention, an excellent functional outcome can be expected.

Microvascular blood flow in normal and pathologic rotator cuffs.

BACKGROUND: Microvascular blood flow in the tendon plays an important role in the pathogenesis of rotator cuff abnormalities. There are conflicting views about the presence of a hypovascular zone in the supraspinatus tendon. Besides, no studies have looked at the pattern of blood flow around a partial-thickness tear. Our aim was to measure microvascular blood flow in normal and a range of pathologic rotator cuff tendons using laser doppler flowmetry. METHODS: A total of 120 patients having arthroscopic shoulder surgery were divided into 4 equal groups on the basis of their intraoperative diagnosis: normal rotator cuff, subacromial impingement syndrome, and partial-thickness or full-thickness rotator cuff tear. Microvascular blood flow was measured at 5 different regions of each cuff using a laser doppler probe. The values were compared to assess variability within and between individuals. RESULTS: Total blood flow was greater in the normal rotator cuff group compared with the groups with pathologic rotator cuffs, with the largest difference seen in the subacromial impingement group. Within individuals, blood flow was highest at the musculotendinous junction and lowest at the lateral insertional part of the tendon. Among groups, the blood flow was significantly lower at the anteromedial and posteromedial cuff in the groups with impingement and full-thickness tears compared with the group with normal cuff. CONCLUSION: Real-time in vivo laser doppler analysis has shown that microvascular blood flow is not uniform throughout the supraspinatus tendon. Blood flow in the pathologic supraspinatus tendon was significantly lower compared with the normal tendon.

The incidence and risk factors for blood transfusion in revision shoulder arthroplasty: our institution's experience and review of the literature.

HYPOTHESIS: The purposes of this study were to determine the incidence of blood transfusion after revision shoulder arthroplasty and to assess risk factors associated with an increased risk of transfusion. MATERIALS AND METHODS: Between 1994 and 2008, 566 consecutive revision shoulder procedures were performed at our institution, which formed the basis of this study. The patient's age, sex, body mass index, comorbidities, preoperative and postoperative hemoglobin level, details of the surgery, operative time, and transfusion details were documented retrospectively from medical records. RESULTS: Overall, 11.3% of patients (64 of 566) required a transfusion. An increased transfusion rate was associated with age (odds ratio [OR] per 10 years, 1.5 [95% confidence interval (CI), 1.2 to 2.0]; P = .002), operative time (≤ 5 hours vs >5 hours) (OR, 3.3 [95% CI, 1.9 to 5.8]; P < .001), diabetes (OR, 2.3 [95% CI, 1.2 to 4.4]; P = .01), and cardiac disease (OR, 2.7 [95% CI, 1.5 to 5.0]; P < .001). There were significant associations between preoperative hemoglobin level (OR, 0.4 per 1 point [95% CI, 0.3 to 0.5]; P < .001) and a decreased odds of transfusion. The type of surgery (surgery on humeral component) also had an impact on the need for transfusion (P < .001). CONCLUSIONS: Older age, low preoperative hemoglobin level, increased operative time, diabetes, presence of cardiac disease, and type of revision surgery are associated with higher postoperative transfusion rates. These factors should be taken into consideration to more accurately predict the need for transfusion and modify preoperative blood-ordering protocols.

The value of intraoperative histology in predicting infection in patients undergoing revision elbow arthroplasty.

BACKGROUND: The perioperative diagnosis of infection in the setting of revision elbow arthroplasty may be difficult to establish. Intraoperative pathology with histology for identification of acute inflammatory changes has been reported to be of value in revision surgery after failed hip or knee arthroplasty. The purpose of this study was to study the role of intraoperative histology in the diagnosis of infection in patients undergoing revision elbow arthroplasty. METHODS: From 2000 to 2007, 296 consecutive revision elbow procedures were performed at our institution. Both intraoperative histology and operative samples for culture were obtained at the time of 227 of these procedures, which form the basis of this study. RESULTS: Histology was read as consistent with acute inflammation in patients undergoing thirty-three procedures (14.5%). Intraoperative cultures were positive in thirty-nine procedures (17.2%). Intraoperative histology was considered true positive (both histology and cultures positive) in twenty arthroplasties (8.8%), true negative (both histology and cultures were negative) in 175 arthroplasties (77.1%), false positive (the histology was positive but the culture was negative) in thirteen arthroplasties (5.7%), and false negative (the histology was negative but the culture was positive) in nineteen arthroplasties (8.4%). With regard to intraoperative histology, the sensitivity was 51.3%, the specificity was 93.1%, and the accuracy was 85.9%. The positive predictive value was 60.6% and the negative predictive value was 90.2%. CONCLUSIONS: In our study, intraoperative histology had a high specificity and negative predictive value, but a low sensitivity and positive predictive value for predicting infection in the setting of revision elbow arthroplasty. Intraoperative histology should be used in conjunction with other studies to definitively establish the diagnosis of infection in the setting of revision elbow arthroplasty. LEVEL OF EVIDENCE: Diagnostic level I. See Instructions for Authors for a complete description of levels of evidence.

Fixation and durability of a bone-ingrowth component for glenoid bone loss.

BACKGROUND: Deficient glenoid bone is a reconstructive challenge in shoulder arthroplasty. One solution is an ingrowth anatomic glenoid with column and screw fixation, with or without supplemental bone graft. This study examines the outcome of patients managed in this manner. MATERIALS AND METHODS: This type of glenoid component was used in 21 shoulder arthroplasties with central or peripheral glenoid bone deficiencies: 13 for bone loss due to arthritic wear and 8 for revision arthroplasty. Patients were monitored clinically for a mean of 11.1 years (range, 7.6-15.1 years) and by x-ray imaging for a mean of 9.1 years (range, 2.2-14.2 years). RESULTS: Revision procedures were needed for 7 shoulders at a mean of 10.4 years (range 5.5-14.3 years), 6 for polyethylene or metal wear leading to glenoid loosening in 4. In the 14 nonrevised shoulders, pain ratings (1 to 5 scale) decreased from a mean of 4.5 to 1.9 (P < .001). Mean active elevation increased from 100° to 125° (P = .02). Mean external rotation increased from 28° to 43° (P = .06). Results assessed by the Neer rating were excellent in 3, satisfactory in 10, and unsatisfactory in 1. In radiographic assessment of the unrevised shoulders, 4 were at risk for glenoid loosening, and 1 was at risk for humeral loosening. CONCLUSIONS: This method of reconstruction can offer pain relief and improved motion. However, the large number of revision procedures and additional adverse changes on x-ray imaging suggest other reconstructive options may be more successful and durable.

Patient reported activities after reverse shoulder arthroplasty: part II.

BACKGROUND: Reverse shoulder arthroplasty (RSA) is becoming a commonly performed procedure. Surgeons are advised to select older patients with lower demands. This study defines patient reported activities following RSA. MATERIALS AND METHODS: Seventy-eight patients with 81 treated shoulders (average age 73 years; 49 women, 32 men) completed a survey asking about clinical parameters: pain, motion, strength, and 72 different activities. Diagnoses were rotator cuff tear arthropathy in 70 shoulders, massive rotator cuff tears with psuedoparalysis in 6, and failed treatment for proximal humeral fractures in 5. Average time from surgery to survey was 3.6 years (range, 3-5). RESULTS: All clinical parameters were favorable. The 3 most commonly reported activities were low demand (cooking, baking, and driving), medium demand (gardening, leaf raking, and lawn mowing), and high demand (snow shoveling, wheelbarrow use, and dirt shoveling). These were comparable to the activities reported for total shoulder arthroplasty and hemiarthroplasty. There was no clinical or activity difference between those components with a lateral or a medial center of rotation. CONCLUSION: A significant proportion of patients continue medium or high demand activities following RSA. These are similar to other types of shoulder arthroplasties. Future studies to determine the safety level of different activities would be helpful to counsel patients accordingly.

The current hospital costs of treating hip fractures.

Hip fractures impact heavily on our health service resources yet there is no recent United Kingdom study detailing hospital costs for such injuries. A comprehensive analysis of 100 patients admitted with a hip fracture was performed to determine current medical expenditure incurred during acute hospitalisation for hip fracture during 2003. Costs associated with surgery (implant and theatre costs) and laboratory/radiological investigations were established from individual use. The mean stay of the study group (mean age 83 years, 77 females and 23 males) was 23 days. The mean total hospital expenditure per patient was calculated to be 12,163 pounds sterling of which ward costs contributed 84%, operative costs 9% and investigations 7%. These results emphasise the growing economic impact arising from the inpatient treatment hip fractures, most of which relate to length of hospital stay.